Yayun Liang Selected Research

Phosphatidylserines

1/2019	APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice.
1/2018	A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts.

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Yayun Liang Research Topics

Disease

27	Neoplasms (Cancer) 02/2022 - 08/2003
26	Breast Neoplasms (Breast Cancer) 02/2022 - 08/2003
7	Neoplasm Metastasis (Metastasis) 01/2019 - 02/2005
4	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 12/2002
2	Triple Negative Breast Neoplasms 01/2019 - 01/2017
2	Breast Diseases (Breast Disease) 08/2012 - 10/2007
1	Ovarian Neoplasms (Ovarian Cancer) 01/2023
1	Ovarian Epithelial Carcinoma 01/2023
1	Ischemia 01/2011
1	Lymphatic Metastasis 09/2010

Drug/Important Bio-Agent (IBA)

18	Estrogens (Estrogen)FDA Link 01/2019 - 08/2003
15	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 02/2005
13	Proteins (Proteins, Gene)FDA Link 01/2018 - 02/2005
13	Progestins (Progestagens)IBA 01/2017 - 02/2005
12	Hormones (Hormone)IBA 02/2022 - 08/2003
8	Progesterone CongenersIBA 01/2017 - 02/2005
7	Estrogen ReceptorsIBA 02/2022 - 08/2003
6	CholesterolIBA 01/2023 - 07/2014
6	Ro 48-8071IBA 01/2023 - 04/2011
6	EnzymesIBA 01/2023 - 07/2014
6	Progesterone Receptors (Progesterone Receptor)IBA 01/2019 - 02/2005
6	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 01/2017 - 10/2007
5	2,2- bis(hydroxymethyl)- 1- azabicyclo(2,2,2,)octan- 3- oneIBA 04/2011 - 10/2007
4	FumaratesIBA 01/2023 - 07/2014
4	lanosterol synthaseIBA 01/2023 - 07/2014
4	LigandsIBA 02/2022 - 02/2005
4	Fulvestrant (Faslodex)FDA Link 09/2009 - 04/2004
3	Norethindrone (Norethisterone)FDA LinkGeneric 01/2017 - 09/2010
3	SteroidsIBA 01/2016 - 09/2006
3	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2015 - 01/2012
3	Messenger RNA (mRNA)IBA 10/2014 - 02/2005
3	Estradiol (Delestrogen)FDA LinkGeneric 09/2010 - 04/2004
3	Thrombospondin 1IBA 09/2009 - 04/2004
3	Mifepristone (RU 486)FDA Link 09/2006 - 12/2002
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2006 - 02/2005
2	lissamine rhodamine B (sulforhodamine B)IBA 02/2022 - 07/2014
2	Estrogen Receptor betaIBA 02/2022 - 10/2007
2	eprenetapoptIBA 01/2019 - 01/2018
2	PhosphatidylserinesIBA 01/2019 - 01/2018
2	LuteolinIBA 01/2017 - 01/2015
2	Aldehyde DehydrogenaseIBA 01/2017 - 01/2015
2	FlavonoidsIBA 01/2015 - 08/2012
2	AndrogensIBA 10/2014 - 12/2002
2	Conditioned Culture MediaIBA 09/2009 - 08/2005
2	Tamoxifen FDA LinkGeneric 12/2005 - 12/2002
1	liquiritigeninIBA 02/2022
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2019
1	Tumor Suppressor Protein p53IBA 01/2018
1	Androgen Receptors (Androgen Receptor)IBA 01/2016
1	ImmunosorbentsIBA 01/2015
1	Simvastatin (Zocor)FDA LinkGeneric 07/2014
1	Fluvastatin FDA Link 07/2014
1	Antineoplastic Agents (Antineoplastics)IBA 01/2013
1	3- (5'- hydroxymethyl- 2'- furyl)- 1- benzylindazoleIBA 01/2013
1	ApigeninIBA 08/2012
1	RANK LigandIBA 08/2012
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2012
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2012
1	Small Interfering RNA (siRNA)IBA 12/2011
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 12/2011
1	Complement System Proteins (Complement)IBA 12/2011
1	Adenosine Triphosphate (ATP)IBA 12/2011
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2011
1	Monoclonal AntibodiesIBA 01/2011
1	Therapeutic UsesIBA 01/2011
1	Progesterone FDA LinkGeneric 09/2010
1	Norgestrel (DL-Norgestrel)FDA LinkGeneric 09/2010
1	Extracellular Matrix ProteinsIBA 09/2009
1	Angiogenesis InhibitorsIBA 10/2007
1	matrigelIBA 10/2007
1	Estrogen Receptor alphaIBA 10/2007
1	progesterone receptor BIBA 12/2005
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 08/2005
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2005
1	afimoxifene (hydroxytamoxifen)IBA 08/2003
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 08/2003
1	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2002

Therapy/Procedure

17	Therapeutics 02/2022 - 08/2003
6	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2017 - 08/2005
3	Contraception (Birth Control) 09/2010 - 08/2005
2	Drug Therapy (Chemotherapy) 01/2019 - 01/2016
1	Castration 01/2016
1	Aftercare (After-Treatment) 01/2011
1	Injections 09/2010
1	Estrogen Replacement Therapy 10/2007